Is celexa stimulating or sedating
When withdrawing treatment on completion or otherwise, reduce the dose gradually over at least 4 weeks to avoid discontinuation symptoms.
After a week, if the patient tolerates the medication, the dose can be increased.Citalopram is a relatively weak inhibitor of CYP2D6 compared with the other SSRIs, and thus it interacts with a more limited range of drugs than fluoxetine and paroxetine.The most important interactions are those with other drugs that affect serotonergic neurotransmission as these can lead to serotonin toxicity and, in severe cases, serotonin syndrome Features of serotonin toxicity (see Table 4) may be relatively mild, such as tremor and low grade restlessness. Serotonin syndrome is the most severe form of serotonin toxicity characterised by a recognised cluster of prominent and severe clinical features that usually require supportive management and stopping the causative agent(s).Choice of antidepressant is also based on individual patient factors.If a patient has responded well to an antidepressant in the past then that drug should be considered first choice. epilepsy, cardiovascular disease and bipolar disorder will also influence choice.